New York in the 1920s. Max Perkins, literary editor at Scribner’s Sons is the first to sign such subsequent literary greats as Ernest Hemingway and F. Scott Fitzgerald. When a sprawling, chaotic 1,000-page manuscript by an unknown writer named Thomas Wolfe falls into his hands, Perkins is convinced he has discovered a literary genius. Together the two men set out to work on a version for publication and a seemingly endless struggle over every single phrase ensues. During this process, Perkins the gentle family man and Wolfe the eccentric author become close – a relationship eyed with suspicion by their wives. When ‘Look Homeward, Angel’ becomes a resounding success, the writer grows increasingly paranoid.